It is possible that the TCAB1-mediated “switch” is not really captured through the conformation characterized within the cryo-EM structure. Characterizing a greater fraction in the holoenzyme particles during the Energetic chromatographic portion will likely lead to the identification of additional conformational states. The cryo-EM characterization of human telomerase also reveals https://o-uk-psikolo-u-olan-hasta19629.digitollblog.com/28144451/5-easy-facts-about-plazma-pen-bursa-described