Inhibition of focal adhesion kinase (FAK) rescued SERT functionality in synapses of KI mice, demonstrating that constitutive Energetic FAK signaling downstream of the Pro32Pro33 integrin αvβthree suppresses SERT activity. Our experiments discover a complex regulation of five-HT homeostasis and behaviors by integrin αvβ3, revealing a crucial position for integrins in https://collinsc321tjx9.birderswiki.com/user