Fragile X Messenger Ribonucleoprotein (FMRP) is necessary for experience-dependent. developmental synapse elimination and the loss of this process may underlie the excess dendritic spines and hyperconnectivity of cortical neurons in Fragile X Syndrome. a common inherited form of intellectual disability and autism. Little is known of the signaling pathways that regulate synapse elimina... https://www.markbroyard.com/hot-deal-jolly-rancher-filled-gummies-7oz-online-hot-sale-big-sale/