Butabarbital will minimize the level or outcome of fedratinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Effect of coadministering a powerful CYP3A4 inducer with fedratinib hasn't been analyzed. butabarbital will lower the level or effect of pioglitazone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance https://kedarj789uqm6.evawiki.com/user